The "US GTM" Playbook: 25 US Venture Builders Backing Indian Startups

Why Your US Expansion Will Fail (And the 1% Playbook to Succeed).

You have traction, a solid team, and a working website. You're ready to scale. But 99% of Indian founders fail at this next step: expanding to the US market.

The common mistake? Pitching US VCs cold. Your deck is dying in their inbox because you haven't solved the "GTM (Go-to-Market) gap."

Here's the truth: The smartest Indian founders are using a "secret on-ramp." They partner with US Venture Builders first. These programs aren't just about a cheque; they are a "GTM-in-a-box." They provide the infrastructure, customer networks, and playbooks to get your first 10 US customers and "de-risk" you for top-tier VCs. This is your strategic map to that on-ramp.

25 US Venture Builders Backing Indian Startups

We've organized this list into the 5 key sectors you're building for

  1. AI-First Startups

  2. B2B Saas Startups

  3. HealthTech Startups

  4. Climate Tech

  5. D2C & Consumer Startups

For AI-First Startups

Venture Builder Name

Typical Check & Model

Their "US GTM" Superpower

Who They Actually Want

How to Apply

Y Combinator

$500k total ($125k for 7% + $375k MFN)

The ultimate "Demo Day" signal. Unrivaled alumni network (9,000+ founders) for fundraising & advice.

Ambitious founders ("Make something people want"). (AI-first teams are a major 2025 focus).

Apply online. Do NOT seek warm intros. A clear, concise app & 1-min video are all that matter.

AI Fund

Co-founds (Venture Studio). Provides up to $1M pre-seed.

"GTM-in-a-Box" for AI. An embedded "tiger team" of ML engineers & data scientists works with you.

Domain-expert founders (often pre-idea) who want to be CEO. They pair you with their in-house AI talent.

Pitch idea via their site. They recruit "Founders in Residence" year-round, not a cohort model.

AI2 Incubator

Up to $600k seed funding on a SAFE.

Full-stack AI support. Embedded PhD-level experts & enterprise customer intros to accelerate PMF.

Applied AI startups (pre-seed/seed) tackling real industries (health, finance, etc.). Global teams welcome.

Online application (rolling). Remote-friendly program based in Seattle.

OpenAI Startup Fund

$1M equity investment. (Converge Program)

Early access to new OpenAI models and 1-on-1 advice from OpenAI engineers and researchers.

"AI natives" (engineers, researchers) using AI in transformative ways. (Pre-idea solo founders accepted).

Apply to "Converge" online. Annual cohorts. Remote-friendly with a final on-site week in SF.

Antler (US)

$200k for 8% + $300k follow-on available.

"Co-founder matching." A 6-week "sprint" to find a co-founder and validate an idea from zero.

"Wired differently" builders. Relentless individuals (often solo) with a "spike" in tech or business.

Apply online for the US Residency (in-person in NY, Austin, SF). No warm intro needed.

For B2B SaaS Startups

Venture Builder Name

Typical Check & Model

Their "US GTM" Superpower

Who They Actually Want

How to Apply

Alchemist Accelerator

$25k for ~5% equity. (6-month program)

The "Enterprise Playbook." "Customer Blitz" sessions give direct intros to Global 2000 buyers.

B2B Enterprise Only. Must monetize from businesses. Prefers distinctive, technical founding teams.

Apply online for cohorts. Acceptance is tough (<5%). Part-time friendly.

Techstars

$220k total ($20k for 5% + $200k MFN SAFE).

Global mentor network (7,000+). An "instant GTM tribe" in every major US city for B2B customer discovery.

"Team, Team, Team." Strong founding teams (Seed) in B2B SaaS, FinTech, etc., ready to leverage mentorship.

Apply online to a specific themed/city program. (e.g., Techstars NYC, Techstars AWS).

500 Global

$150k for 6% (minus program fees).

"Growth Hacks" Curriculum. Deep focus on growth marketing (SEO, virality, sales funnels) from in-house experts.

Scrappy global founders (SaaS, FinTech) with a product & some traction, ready for a US launch.

Apply online for the Flagship Accelerator (Palo Alto). They love founders from emerging markets.

Forum Ventures

$100k for ~8%. (Remote-friendly)

"Fractional co-founder" approach. Partners act like extended team, joining sales calls & strategy.

Pre-seed B2B SaaS & AI startups. Prefers teams with domain expertise in their industry.

Apply online for 3 cohorts/year. Remote-first. Be ready for intensive, hands-on help.

High Alpha

Co-founds (Venture Studio). Equity varies.

B2B SaaS GTM-in-a-Box. A cross-functional team of GTM & brand experts co-builds with you.

First-time or seasoned founders with deep experience in B2B SaaS, ready to co-create.

"Get In Touch" via their "Build With Us" page. This is a rolling partnership, not a cohort.

FalconX (Silicon Valley)

Up to $100k (via fund) for select startups.

"Soft-landing" in the US. Tailor-made for Indian B2B SaaS. Provides free office space & "Technology Day" showcase.

Post-revenue Indian SaaS companies with an MVP, ready to "land and expand" in the US.

Apply online for the Global Immersion cohort. Starts virtual, then 5-week on-site in Milpitas, CA.

For HealthTech Startups

Venture Builder Name

Typical Check & Model

Their "US GTM" Superpower

Who They Actually Want

How to Apply

IndieBio (SOSV)

$250k initial for ~8% + $275k follow-on.

Biotech Bootcamp + Labs. Provides full wet lab access & in-house scientists to build your prototype.

"Hard-science" (BioTech, DeepTech) PhDs or science teams. Often pre-seed with just a research paper.

Apply online (rolling). Must relocate to SF or NY lab for 4 months. Show your scientific novelty.

Dreamit Health

$50k uncapped SAFE. (Secures rights to invest later).

Enterprise Healthcare Pipeline. "Customer Sprints" set up curated pitches to 70+ US health systems & payors.

Revenue-stage Health IT, MedTech, or Digital Health (min. $10k MRR or active pilots).

Apply online (rolling). Remote program. Must have a product ready for enterprise discussions.

Startup Health

$100k SAFE. (12-24 month program, not a cohort).

"Health Transformer" Platform. A decade-long commitment. Continuous coaching & global health network.

Mission-driven founders (Seed) tackling big "health moonshots" (Cure Disease, Women's Health, etc.).

Apply online (rolling). Admits new companies quarterly. Mostly virtual.

Techstars Healthcare (LA)

$220k total (Techstars standard deal).

Clinical Validation & Hospital Access. Backed by Cedars-Sinai & other hospitals for direct pilot programs.

MedTech & Digital Health startups ready to pilot. (AI diagnostics, remote monitoring, etc.).

Apply via Techstars (LA Healthcare). Must relocate to LA for 3 months.

Plug and Play Health

$0 equity to join. (Optional $150k investment).

Connector to Big Pharma & Health Giants. A match-maker for pilots with 200+ partners (J&J, Anthem, Kaiser).

Any stage (prototype to Series B). Must have a clear use case for their corporate partners.

Apply online (select "Health"). Must have a clear B2B use case for a corporate partner.

For HealthTech Startups

Venture Builder Name

Typical Check & Model

Their "US GTM" Superpower

Who They Actually Want

How to Apply

IndieBio (SOSV)

$250k initial for ~8% + $275k follow-on.

Biotech Bootcamp + Labs. Provides full wet lab access & in-house scientists to build your prototype.

"Hard-science" (BioTech, DeepTech) PhDs or science teams. Often pre-seed with just a research paper.

Apply online (rolling). Must relocate to SF or NY lab for 4 months. Show your scientific novelty.

Dreamit Health

$50k uncapped SAFE. (Secures rights to invest later).

Enterprise Healthcare Pipeline. "Customer Sprints" set up curated pitches to 70+ US health systems & payors.

Revenue-stage Health IT, MedTech, or Digital Health (min. $10k MRR or active pilots).

Apply online (rolling). Remote program. Must have a product ready for enterprise discussions.

Startup Health

$100k SAFE. (12-24 month program, not a cohort).

"Health Transformer" Platform. A decade-long commitment. Continuous coaching & global health network.

Mission-driven founders (Seed) tackling big "health moonshots" (Cure Disease, Women's Health, etc.).

Apply online (rolling). Admits new companies quarterly. Mostly virtual.

Techstars Healthcare (LA)

$220k total (Techstars standard deal).

Clinical Validation & Hospital Access. Backed by Cedars-Sinai & other hospitals for direct pilot programs.

MedTech & Digital Health startups ready to pilot. (AI diagnostics, remote monitoring, etc.).

Apply via Techstars (LA Healthcare). Must relocate to LA for 3 months.

Plug and Play Health

$0 equity to join. (Optional $150k investment).

Connector to Big Pharma & Health Giants. A match-maker for pilots with 200+ partners (J&J, Anthem, Kaiser).

Any stage (prototype to Series B). Must have a clear use case for their corporate partners.

Apply online (select "Health"). Must have a clear B2B use case for a corporate partner.

For ClimateTech & Sustainability Startups

Venture Builder Name

Typical Check & Model

Their "US GTM" Superpower

Who They Actually Want

How to Apply

Third Derivative (D3)

$100k convertible note (optional). (18-month program).

Unparalleled Climate Ecosystem. Founded by RMI (Rocky Mountain Institute) for 700+ energy expert advisors.

"HardTech" or "DeepTech" Climate startups (new batteries, carbon capture, grid tech). Must have a prototype.

Apply online (annual call). Remote program. Highlight your CO2 reduction potential (gigatons).

HAX (SOSV Hard Tech)

$250k initial SAFE for ~10% + $5M follow-on.

Prototyping & Manufacturing. In-house R&D team (Mech/Elec engineers) builds prototypes with you.

"Hard Tech" (Hardware/IoT) in Climate, AgTech, Robotics. Must have a prototype or lab PoC.

Apply online (rolling). Relocate to Newark, NJ, or Shenzhen, China. A video of your prototype helps.

Elemental Excelerator

Non-dilutive funding up to $1M (as a grant).

Deployment-Driven Pilots. They pay for and project-manage your first real-world pilot (often in HI or CA).

Post-Series A (or high-traction Seed) ready to scale a real-world deployment.

Apply online (annual cohort). Remote program. Must be ready to deploy a project.

The Engine (MIT)

$250k - $2M seed (leads round).

"Tough Tech" Launchpad. Provides physical labs (wet labs, machine shops) & access to MIT's network.

Pioneering "Tough Tech" scientists (PhD-founders) in Climate, Bio, Quantum. Often pre-revenue.

Apply online (annual cohort). Must relocate to Cambridge, MA, to use the labs.

MassChallenge

$0 equity. (Compete for non-dilutive grants).

Validation & Corporate Access. An equity-free way to "soft-land" in the US & get intros to 250+ partners.

High-impact startups (any sector) with <$1M raised. (They have dedicated Climate & Health tracks).

Apply online (annual cohorts in Boston, Houston, etc.). It's a competition, not a guaranteed investment.

For ClimateTech & Sustainability Startups

Venture Builder Name

Typical Check & Model

Their "US GTM" Superpower

Who They Actually Want

How to Apply

Third Derivative (D3)

$100k convertible note (optional). (18-month program).

Unparalleled Climate Ecosystem. Founded by RMI (Rocky Mountain Institute) for 700+ energy expert advisors.

"HardTech" or "DeepTech" Climate startups (new batteries, carbon capture, grid tech). Must have a prototype.

Apply online (annual call). Remote program. Highlight your CO2 reduction potential (gigatons).

HAX (SOSV Hard Tech)

$250k initial SAFE for ~10% + $5M follow-on.

Prototyping & Manufacturing. In-house R&D team (Mech/Elec engineers) builds prototypes with you.

"Hard Tech" (Hardware/IoT) in Climate, AgTech, Robotics. Must have a prototype or lab PoC.

Apply online (rolling). Relocate to Newark, NJ, or Shenzhen, China. A video of your prototype helps.

Elemental Excelerator

Non-dilutive funding up to $1M (as a grant).

Deployment-Driven Pilots. They pay for and project-manage your first real-world pilot (often in HI or CA).

Post-Series A (or high-traction Seed) ready to scale a real-world deployment.

Apply online (annual cohort). Remote program. Must be ready to deploy a project.

The Engine (MIT)

$250k - $2M seed (leads round).

"Tough Tech" Launchpad. Provides physical labs (wet labs, machine shops) & access to MIT's network.

Pioneering "Tough Tech" scientists (PhD-founders) in Climate, Bio, Quantum. Often pre-revenue.

Apply online (annual cohort). Must relocate to Cambridge, MA, to use the labs.

MassChallenge

$0 equity. (Compete for non-dilutive grants).

Validation & Corporate Access. An equity-free way to "soft-land" in the US & get intros to 250+ partners.

High-impact startups (any sector) with <$1M raised. (They have dedicated Climate & Health tracks).

Apply online (annual cohorts in Boston, Houston, etc.). It's a competition, not a guaranteed investment.

For D2C & Consumer Startups

Venture Builder Name

Typical Check & Model

Their "US GTM" Superpower

Who They Actually Want

How to Apply

XRC Labs (NYC)

$100k - $300k pre-seed for ~5-6%.

Retail & Brand Insiders. Unmatched access to partners (Estee Lauder, Mastercard) for pilots.

Next-gen Consumer & Retail (Beauty, Food, Apparel). Must have a prototype or early revenue.

Apply online (two cohorts/year). Hybrid program based in NYC.

Science Inc. (LA)

$250k - $500k (Studio model). (20-40% equity).

Brand-Building Machine. The team behind Dollar Shave Club & MeUndies. A 100+ person growth team "on tap."

Digitally native brands with stellar unit economics. (Loves subscription models & CPG).

Referral or pitch deck. This is a studio partnership, not a cohort. Works from Los Angeles.

SKU Accelerator (CPG)

No cash. (1-5% equity warrant).

CPG Scale-up Playbook. Deep curriculum on retail distribution, packaging, & brand story.

In-market CPG brands with ≥$100K annual revenue. (Food/Bev, Beauty, Pet, Apparel).

Apply online (cohorts in Austin, Dallas, etc.). Must have existing sales traction.

LAUNCH Accelerator

$100k for 6% equity. (12-week program).

Massive Media Reach. A stage on "This Week in Startups" podcast & access to the LAUNCH Syndicate.

Scrappy B2C or subscription app founders with a product in market and some traction/revenue.

Apply via LAUNCH website (rolling). Be ready for weekly online pitches (Jason can be blunt!).

On Deck (ODF)

$0 equity. (Fellowship program, not a fund).

Founder Network on Steroids. Lifetime access to a 3,000+ member community to find co-founders & beta customers.

Aspiring founders (ex-FAANG, 2nd-time founders) who are pre-idea or pre-team.

Apply online (cohorts run ~3x/year). 1-week in-person (SF) + lifetime virtual access.

For D2C & Consumer Startups

Venture Builder Name

Typical Check & Model

Their "US GTM" Superpower

Who They Actually Want

How to Apply

XRC Labs (NYC)

$100k - $300k pre-seed for ~5-6%.

Retail & Brand Insiders. Unmatched access to partners (Estee Lauder, Mastercard) for pilots.

Next-gen Consumer & Retail (Beauty, Food, Apparel). Must have a prototype or early revenue.

Apply online (two cohorts/year). Hybrid program based in NYC.

Science Inc. (LA)

$250k - $500k (Studio model). (20-40% equity).

Brand-Building Machine. The team behind Dollar Shave Club & MeUndies. A 100+ person growth team "on tap."

Digitally native brands with stellar unit economics. (Loves subscription models & CPG).

Referral or pitch deck. This is a studio partnership, not a cohort. Works from Los Angeles.

SKU Accelerator (CPG)

No cash. (1-5% equity warrant).

CPG Scale-up Playbook. Deep curriculum on retail distribution, packaging, & brand story.

In-market CPG brands with ≥$100K annual revenue. (Food/Bev, Beauty, Pet, Apparel).

Apply online (cohorts in Austin, Dallas, etc.). Must have existing sales traction.

LAUNCH Accelerator

$100k for 6% equity. (12-week program).

Massive Media Reach. A stage on "This Week in Startups" podcast & access to the LAUNCH Syndicate.

Scrappy B2C or subscription app founders with a product in market and some traction/revenue.

Apply via LAUNCH website (rolling). Be ready for weekly online pitches (Jason can be blunt!).

On Deck (ODF)

$0 equity. (Fellowship program, not a fund).

Founder Network on Steroids. Lifetime access to a 3,000+ member community to find co-founders & beta customers.

Aspiring founders (ex-FAANG, 2nd-time founders) who are pre-idea or pre-team.

Apply online (cohorts run ~3x/year). 1-week in-person (SF) + lifetime virtual access.

The GTM Match Matrix: Find Your Perfect US Venture Builder.

The final, actionable step is to self-diagnose the startup's primary need and map it to the optimal GTM on-ramp. The following matrix provides a clear decision-making framework for Indian founders as of November 2025.

Founder Profile / Primary Need

Your Primary GTM Need

GTM Archetype to Target

Programs to Target

"I am a solo founder with strong domain expertise but no US-based co-founder, idea, or team."

Co-Founder & Idea Validation

The "Day Zero" Co-Founder

Antler (US), On Deck (ODF)

"I have a deep tech / AI R&D background but no business co-founder or in-house GTM/product team."

In-House GTM & Product Team

The Venture Studio (AI)

AI Fund, AI2 Incubator

"I have a proven B2B SaaS product in India and need to acquire my first 10-20 US enterprise customers."

Enterprise Customer Access

The Enterprise Playbook or The Corporate Pilot

Alchemist Accelerator, Plug and Play Health

"I have strong traction and a polished product (B2B or B2C) and need US VC validation to lead a large seed round."

VC Signal & Fundraising

The Signal

Y Combinator, Techstars

"I have a high-traction B2B SaaS company and need an experienced US operator to help me co-found the US entity."

B2B SaaS GTM Co-Founder

The Venture Studio (B2B)

High Alpha, Forum Ventures

"I have 'tough tech' (hardware, robotics, or deep science) and need to build a prototype."

"Tough Tech" R&D / Validation

The Deep Tech Accelerator

HAX (SOSV), IndieBio (SOSV)

"I am just starting. I need to incorporate in the US, open a US bank account, and get a 'soft landing'."

Legal & GTM Infrastructure

The "Soft-Landing" Accelerator

FalconX (Silicon Valley), Antler (US)

The "How to Win" Summary: From GTM to Growth.

The path to US expansion is a clear, multi-step process. For most Indian founders, the journey doesn't start with a VC. It starts with a strategic "on-ramp."

If you are a B2B SaaS founder, your "on-ramp" is the Alchemist Accelerator (for enterprise customers) or Plug and Play (for corporate pilots). If you are a DeepTech founder, it's IndieBio or HAX (for labs and validation). If you have high traction and are ready to raise, Y Combinator is your "VC Signal."

This list is your "who." The "how" is just as critical. Fundraising is a process of managing dozens of conversations, tracking follow-ups, and building momentum. At Backrr, we built the fundraising Operating System to help you manage this exact process. You can use this list to build your target pipeline on our platform, manage your outreach, and turn these first conversations into your final term sheet.

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